Biopharmaceuticals: pharmacokinetics and pharmacodynamics

Conducted by: Prof. David Stepensky

SKU: 24956

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The course outline:

Mechanisms of drug absorption, distribution and elimination
Pharmacokinetic (PK) and pharmacodynamic (PD) relationships
Major PK and PK/PD models:
- Non-compartmental PK analysis
- Compartmental PK analysis
- Physiologically-based PK modeling
- Population PK modeling
- PK/PD models (Emax, indirect response, etc.)
- PK/PD modeling of biopharmaceuticals
PK and PK-PD modeling and its use in pre-clinical and clinical...Continue reading

The course outline:

Mechanisms of drug absorption, distribution and elimination
Pharmacokinetic (PK) and pharmacodynamic (PD) relationships
Major PK and PK/PD models:
- Non-compartmental PK analysis
- Compartmental PK analysis
- Physiologically-based PK modeling
- Population PK modeling
- PK/PD models (Emax, indirect response, etc.)
- PK/PD modeling of biopharmaceuticals
PK and PK-PD modeling and its use in pre-clinical and clinical development:
- choice of the model
- model evaluation and assessment
- prediction of disposition and pharmacological activity in animals and humans
Hands-on analysis of specific case studies using scientific software (freely-available program that can be used by the participants after the course)
Demonstration of professional software that can be used for PK and PK analysis
Preliminary analysis of the participant’s own PK and PD data (optional)

Dates:

Course location: Zoom Course

Duration: 1-Day Course

Hours: 09:00 - 12:30

Credits: 1

Course Language: עברית

Course price: ₪1,950 + VAT

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B.Sc., M.Sc. and Ph. D. studies at School of Pharmacy,