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Chiral SeparationEnantioselective HPLC – Method Development
Selected advanced topics for HPLC experts
The seminar focuses on updated and modern approaches for developing an enantioselective method based on the lecturer’s first-hand experience. The classification and application of various chiral (enantioselective) stationary phases are discussed and presented using test cases. If necessary this course can be translated and given in English
Have a question? We have the answer
Issues to be covered
The following issues will be covered:
- Principles of chiral resolution by chiral (enantioselective) stationary phases
- Similarity and differences between various chiral stationary phases
- NP and RP separations in chiral chromatography: advantages and pitfalls
- Limitations in use of organic solvents in NP and RP enantioselective chromatography
- Influence of:
- mobile phase composition
- pH
- temperature
- column type
- etc
- on the chromatographic performance
- Strategy of enantioselective method development for a comparatively simple molecule with only one chiral center (case study)
Who should attend
- Analytical chemists with experience in HPLC or related techniques who work in:
- Quality Control
- Analytical laboratories
- R&D
- Bachelor, master or PhD students who wish to learn and experience modern analytical enantioselective methods
About The Lecturer
Vladimir Ioffe
Vladimir Ioffe, Ph.D., Scientific Expert, Lecturer and Advisor in Pharmaceuticcal
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