Drug products topically administered via the skin fall into two general categories, those applied for local action and those for systemic effects. Local actions include those that exert their actions on the function of the epidermis and/or the dermis. The use of topical medications does not result in significant drug concentrations in the blood and other tissues, and causes fewer...
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Drug products topically administered via the skin fall into two general categories, those applied for local action and those for systemic effects. Local actions include those that exert their actions on the function of the epidermis and/or the dermis. The use of topical medications does not result in significant drug concentrations in the blood and other tissues, and causes fewer adverse reactions. Common products in the former category include creams, gels, ointments, pastes, suspensions, lotions, foams, sprays, aerosols, and solutions.
Transdermal drug delivery systems (TDDSs) are discrete dosage forms that are designed to deliver therapeutically effective amount of drug through intact skin to the systemic circulation. The common drug products applied to the skin for systemic effects are transdermal patches.
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