Topical dermal and transdermal drug delivery systems

Conducted by: Dr. Eva Abramov
SKU: 21921
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Drug products topically administered via the skin fall into two general categories, those applied for local action and those for systemic effects. Local actions include those that exert their actions on the function of the epidermis and/or the dermis. The use of topical medications does not result in significant drug concentrations in the blood and other tissues, and causes fewer...Continue reading

Drug products topically administered via the skin fall into two general categories, those applied for local action and those for systemic effects. Local actions include those that exert their actions on the function of the epidermis and/or the dermis. The use of topical medications does not result in significant drug concentrations in the blood and other tissues, and causes fewer adverse reactions. Common products in the former category include creams, gels, ointments, pastes, suspensions, lotions, foams, sprays, aerosols, and solutions.

Transdermal drug delivery systems (TDDSs) are discrete dosage forms that are designed to deliver therapeutically effective amount of drug through intact skin to the systemic circulation. The common drug products applied to the skin for systemic effects are transdermal patches.

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Dates: 
  • 03/03/2021
  • 04/03/2021
Course location: Zoom Course
Duration: 2 half-day Course (Morning)
Hours: 09:00 - 12:30
Credits: 1
Course Language: עברית

Course price: ₪1,700 + VAT
Early registration is Closed
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Issues to be covered

  • Skin structure and function
    • Major characteristics
    • Structure of the layers
    • Blood vessels
    • Function
    • Routes of Traditional Transdermal Drug Penetration
  • Topical drug delivery
    • Introduction
    • Formulations and manufacturing technologies of different products
    • Excipients in use
    • Advantages and limitations
  • Transdermal Drug Delivery system (TDDS)
    • Introduction
    • Drug candidates
    • Product development and patch design
    • Manufacturing technologies of film casting
    • Excipients in use
    • Advantages and limitations
  • Strategies for penetration enhancing
    • Stratum corneum modification
    • Permeation enhancers
    • Mechanical methods
    • Energy driven methods
    • Microneedles
  • Analytical method for skin penetration determination
    • Franz cell diffusion method
    • Membrane selection
  • Summary

Who should attend

  • Scientists from pharmaceutical industry
  • Team, R&D, Project managers from pharmaceutical industry
  • Scientists, formulators from cosmetic industry
  • Team, R&D, Project managers from cosmetic industry
  • Scientists who wish to integrate the pharmaceutical and cosmetic industry

Benefits to the Participants

The objective of the course is to provide knowledge and understanding of skin physiology, topical and transdermal drug delivery systems, formulations and manufacturing technologies, excipients in use, different strategies for skin penetration enhancing and analytical method for skin penetration determination.

About The Lecturer

Eva Abramov
Dr. Abramov has M.Sc. and B.Sc. degrees in chemistry from
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